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2015年版WHO胸腺及纵隔肿瘤分类

2015年版WHO胸腺及纵隔肿瘤分类

上皮性肿瘤 Epithelial tumours

胸腺瘤(thymomas)

A型胸腺瘤,包括非典型亚型(type A thymoma including atypical variant

AB型胸腺瘤(type AB thymoma)

B1型胸腺瘤(type B1 thymoma)

B2型胸腺瘤(type B2 thymoma)

B3型胸腺瘤(type B3 thymoma)

微小结节性胸腺瘤伴淋巴样间质(micronodular thymoma with lymphoid stroma)

化生型胸腺瘤(metaplastic thymoma)

其它少见胸腺瘤(other rare thymomas

显微镜下胸腺瘤(microscopic thymoma)

硬化型胸腺瘤(sclerosing thymoma)

脂肪纤维腺瘤(lipofibroadenoma)

胸腺癌(包括胸腺神经内分泌上皮肿瘤)(thymic carcinoma)

鳞状细胞癌(squamous cell carcinoma)

基底细胞样癌(basaloid carcinoma)

黏液表皮样癌(mucoepidermoid carcinoma)

淋巴上皮瘤样癌(lymphoepithelioma-like carcinoma)

透明细胞癌 clear cell carcinoma

肉瘤样癌(癌肉瘤)(sarcomatoid carcinoma)

腺癌(adenocarcinoma)

乳头状腺癌(papillary adenocarcinoma)

胸腺癌伴腺样囊腺癌样特征(thymoma with adenoid cystic carcinoma-like features

黏液性腺癌(mucinous adenocarcinoma

腺癌,非特指型(adenomaNOS

NUT癌 (NUT carcinoma

未分化癌undifferentiated carcinomas

其它少见胸腺癌(other rare thymic carcinoma

腺鳞癌adenosquamous carcinoma

肝样癌 hepatoid carcinoma

胸腺癌,非特指型(thymic carcinomaNOS

胸腺神经内分泌肿瘤 thymic neuroendocrine tumours

类癌 carcinoid tumours 

典型类癌 typical carcinoid

不典型类癌 atypical carcinoid

大细胞神经内分泌癌 large cell neuroendocrine  carcinoma

复合大细胞神经内分泌癌combined large cell neuroendocrine  carcinoma

小细胞癌 small cell carcinoma                                 

复合性小细胞癌 combined small cell carcinoma

混合性胸腺癌 (combined thymic carcinoma)


纵膈生殖细胞肿瘤 Germ cell tumours of the mediastinum

精原细胞瘤 seminoma

胚胎性癌embryonal carcinoma

卵黄囊瘤 York sac tumour

绒毛膜癌 choriocarcinoma

畸胎瘤 teratoma

成熟性畸胎瘤 teratoma,mature

不成熟畸胎瘤 teratoma,immature

混合性生殖细胞肿瘤 mixed germ cell tumours

生殖细胞肿瘤伴体细胞型实性恶性成分 germ cell tumour with somatic-type solid malignancy

生殖细胞肿瘤伴相关恶性血液肿瘤 germ cell tumour with associated haemotologic malignancy


纵膈淋巴瘤 lymphoma of the mediastinum

原发性纵隔大B细胞淋巴瘤Primary mediastinal large B-cell lymphoma

黏膜相关淋巴组织结外边缘区淋巴瘤 (MALT淋巴瘤)Extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma)

其它成熟B细胞淋巴瘤 other ature B-Cell lymphoma

淋巴母细胞白血病/淋巴瘤T-ALL/LBL T lymphoblastic leukemia/lymphoma

间变大细胞淋巴瘤和其它少见成熟TNK细胞淋巴瘤Anaplastic large cell lymphoma and other rare mature T- and NK-Cell lymphomas

ALK阳性间变大细胞淋巴瘤ALCL ALK-positive(ALK+)

ALK阴性间变大细胞淋巴瘤ALCL ALK-negative(ALK-)

霍奇金淋巴瘤Hodgkin lymphoma

B细胞淋巴瘤,不能分类,特征介于弥漫大B细胞淋巴瘤与经典型霍奇金淋巴瘤之间

B-cell lymphoma, unclassifiable, with features intermediate between diffuse

large B-cell lymphoma and classical Hodgkin lymphoma


纵膈组织细胞及树状突细胞肿瘤 Histocytic and dendritic cell neoplasms of the mediastinum

朗格罕细胞病变Langerhans cell lesions

朗格罕细胞组织细胞增多症Langerhans cell histiocytosis(LCH)

朗格罕细胞肉瘤Langerhans cell sarcoma(LCS)

组织细胞肉瘤Histiocytic sarcoma

滤泡状树突细胞肉瘤Follicular dendritic cell sarcoma(FDC)

指状突树突细胞肉瘤Interdigitating dendritic cell sarcoma(IDC)

纤维母细胞性网状细胞肿瘤 Fibroblastic reticular cell tumor

未确定的树状突细胞肿瘤Indeterminate dendritic cell tumor


髓系肉瘤和髓外急性髓系白血病Myeloid sarcoma and extramedullary acute myeloid leukemia


纵膈软组织肿瘤 soft tissue tumours of the mediastinum

胸腺脂肪瘤Thymolipoma

脂肪瘤lipoma

脂肪肉瘤liposarcoma

高分化well differentiated

去分化 dedifferentiated

黏液性 myxoid

多形性pleomorphic

孤立性纤维性肿瘤 solitary fibrous tumour

恶性malignant

滑膜肉瘤synovial sarcoma

滑膜肉瘤,非特指型synovial sarcomaNOS

滑膜肉瘤,梭形细胞synovial sarcomaspindle cell

滑膜肉瘤,上皮样细胞synovial sarcomaepithelioid cell

滑膜肉瘤,双向型synovial sarcomabiphasic

脉管肿瘤vascular neoplasms

淋巴管瘤lyphangioma

血管瘤haemangioma

上皮样血管内皮细胞瘤epithelioid hemangioendothelioma

血管肉瘤andiosarcoma

神经源性肿瘤neurogenic tumours

周围神经肿瘤 tumours of peripheral nerve

节细胞神经瘤ganglioneuroma

节细胞神经母细胞瘤ganglioneuroblastoma

神经母细胞瘤neuroblastoma


胸腺异位肿瘤 ectopic tumours of the thymoma

异位甲状腺肿瘤 ectopic thyroid tumours

异位甲状旁腺肿瘤ectopic parathyroid tumours

其它少见异位肿瘤 other rare ectopic tumours


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