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2018年第四版WHO 皮肤肿瘤分类

角化细胞/表皮肿瘤Keratinocytic/epidermal tumours

Carcinomas

基底细胞癌非特指  Basal cell carcinoma NOS 8090/3

结节基底细胞癌Nodular basal cell carcinoma 8097/3

表浅基底细胞癌Superlicial basal cell carcinoma 8091/3

微结节基底细胞癌Micronodular basal cell carcinoma 8097/3

浸润基底细胞癌Infiltrating basal cell carcinoma 8092/3

硬化性基底细胞癌Sclerosing/morphoeic basal cell carcinoma 8092/3

基底鳞状细胞癌Basosquamous carcinoma 8094/3

色素性鳞状细胞癌Pigmented basal cell carcinoma 8090/3

基底细胞癌伴肉瘤样分化

Basal cell carcinoma with sarcomatoid dilferentiation 8092/3

基底细胞癌伴附属器分化

Basal cell carcinoma with adnexal differentiation 8090/3

纤维上皮瘤样基底细胞癌Fibroepithelial basal cell carcinoma 8093/3

鳞状细胞癌非特指型Squamous cell carcinoma NOS 0070/3

角化棘皮瘤Keratoacanthoma 8071/3

棘层松解型鳞状细胞癌Acantholytic squamous cell carcinoma 8075/3

梭形细胞鳞状细胞癌Spindle cell squamous cell carcinoma 8074/3

疣状鳞状细胞癌Verrucous squamous cell carcinoma 8051/3

腺鳞癌Adenosquamous carcinoma 8560/3

透明细胞基底细胞癌Clear cell squamous cell carcinoma 8084/3

其它少见类型Other (uncommon) variants

鳞状细胞癌伴肉瘤样分化

Squamous cell carcinoma with sarcomatoid differentiation 8074/3

淋巴上皮瘤样癌Lymphoepitheliorna-like carcinoma 8082/3

假血管鳞状细胞癌Pseudovascular squamous cell carcinoma 8074/3

鳞状细胞癌伴破骨样巨细胞

Squamous cell carcinoma with osteoclast-like giant cells 8035/3

原位鳞状细胞癌Squamous cell carcinoma in situ (Bowen disease) 8070/2

麦克细胞癌Merkel cell carcinoma8247/3

癌前体和类似恶性前良性角化病

Carcinoma precursors and benign simulants Premalignant keratoses

日光性角化病Actinic keratosis 8070/0"

砷角化病Arsenical keratosis 8070/0

PUVA角化病PUVA keratosis 8070/0*

Verrucae

寻常疣Verruca vulgaris

跖疣Verruca plantaris

扁平疣Verruca plana

良性棘皮瘤/角化病Benign acanthomas/keratoses

脂溢性角化病Seborrhoeic keratosis 8052/0

日光性雀斑Solar lentigo 3052/0

扁平角化苔藓Lichen planus-like keratosis 8052/0

透明细胞棘皮瘤Clear cell acanthoma 8084/0"

大细胞棘皮瘤 Large cell acanthoma 8072/0"

疣状角化不良瘤Warty dyskeratoma 8054/0

其它良性角化病Other benign keratoses 8052/0

黑色素细胞肿瘤Melanocytic tumours

间歇性阳光照射皮肤中的黑色素细胞肿瘤

Melanocytic tumours in intermittently sun-exposed skin

CSO黑色素瘤Low-CSO melanoma

(浅表扩散性黑色素瘤superficial spreading melanoma) 8743/3

单纯性慢状黑素细胞痣

Simple lentigo and lentiginous melanocyticnaevus 8742/0*

交界痣Junctional naevus 8740/0

复合痣Compound naevus8760/0Dermal naevus 8750/0

异型增生痣Dysplastic naevus 8727/0

蜘蛛痣Naevus spilus 8720/0

特殊部位痣Special-site naevi (of the breast, axilla, scalp,and ear)

晕痣Halo naevus 8723/0

梅耶森痣Meyerson naevus 8720/0

复发痣Recurrent naevus

深部穿通痣Deep penetrating naevus 8720/0

色素性上皮样黑色素细胞瘤Pigmented epithelioid melanocytoma 8780/1*

混合性痣Combined naevus, including combined

BAP失活痣/色素细胞瘤

BAP1-inactivated naevus/melanocytoma8720/0

慢性阳光暴露部位皮肤色素细胞肿瘤

Melanocytic tumours in chronically sun-exposed skin

雀斑样恶性黑色素瘤Lentigo maligna melanoma 8742/3

促基结缔组织增生性黑色素瘤Desmoplastic melanoma 8745/3

Spitz肿瘤Spitz tumours

恶性Spitz痣Malignant Spitz tumour (Spitz melanoma)8770/3

Spitz痣Spitz naevus 8770/0

色素性梭形细胞痣Pigmented spindle cell naevus (Reed naevus) 8770/0

肢端皮肤色素细胞肿瘤Melanocytic tumours in acral skin

肢端黑色素瘤Acral melanoma 8744/3

肢端痣Acral naevus 8744/0

生殖道和黏膜黑色素细胞肿瘤Genital and mucosal melanocytic tumours

黏膜黑色素瘤(生殖道、口腔、鼻窦)

Mucosal melanomas (genital, oral, sinonasal) 8720/3

黏膜雀斑黑色素瘤Mucosal lentiginous melanoma 8746/3

黏膜结节性黑色素瘤Mucosal nodular melanoma 8721/3

生殖道痣Genital naevus 8720/0

起源于蓝痣的黑色素细胞肿瘤Melanocytic tumours arising in blue naevus

起源于蓝痣的黑色素瘤Melanoma arising in blue naevus 8780/3

蓝痣非特指型Blue naevus NOS 8780/0

细胞性蓝痣Cellular blue naevus  8790/0

胎记Mongolian spot

伊藤痣Naevus of Ito

太田痣Naevus of Ota

起源于先天性痣的色素细胞肿瘤

Melanocytic tumours arising in congenital naevi

起源于巨大先天性痣的黑色素瘤

Melanoma arising in giant congenital naevus8761/3

先天性色素细胞痣Congenital melanocytic naevus 8761/0

先天性色素细胞痣中的增生结节

Proliferative nodules in congenital melanocytic naevus 8762/1

眼色素细胞肿瘤Ocular melanocytic tumours

葡萄膜黑素瘤Uveal melanoma

上皮样细胞黑色素瘤Epithelioid cell melanoma 8771/3

梭形细胞黑色素瘤,A型Spindle cell melanoma, type A 8773/3

梭形细胞黑色素瘤,B型Spindle cell melanoma, type B 8774/3

结膜黑色素瘤Conjunctival melanoma

黑色素瘤非特指型Melanoma NOS 8720/3

结膜原发性获得性色素细胞增生伴非典型/原位黑色素瘤

Conjunctival primary acquired melanosis with atypia/melanoma in situ 8720/2

结膜痣Conjunctival naevus 8720/0

结节性、痣样和转移性黑色素瘤

Nodular, naevoid, and metastatic melanomas

结节性黑色素瘤Nodular melanoma 8721/3

痣样黑色素瘤Naevoid melanoma 8720/3

转移性黑色素瘤Metastatic melanoma 8720/6

附属器肿瘤Appendageal tumours

恶性肿瘤伴大汗腺和小汗腺化生

Malignant tumours with apocrine and eccrine differentiation

附属器腺癌非特指型Adnexal adenocarcinoma NOS 8390/3

微囊性附属器癌Microcystic adnexal carcinoma 8407/3

汗孔癌Porocarcinoma 8409/3

原位汗孔癌Porocarcinoma in situ3409/2

起源于螺旋腺瘤·、圆柱瘤或螺旋腺圆柱瘤的恶性肿瘤Malignant neoplasms arising from spiradenoma.cylindroma, or spiradenocylindroma8403/3

恶性混合瘤Malignant mixed tumour 8940/3

汗腺癌Hidradenocarcinoma 8402/3

黏液癌Mucinous carcinoma 8480/3

内分泌产粘液汗腺癌

Endocrine mucin-producing sweat gland carcinoma 8509/3

指乳头状汗腺癌Digital papillary adenocarcinoma 8408/3

腺样囊性癌Adenoid cystic carcinoma 8200/3

大汗腺癌Apocrine carcinoma 8401/3

鳞状小汗腺导管癌Squamoid eccrine ductal carcinoma 8560/3

管状乳头状囊腺瘤Syringocystadenocarcinoma papillilerum 8406/3*

分泌性癌Secretory carcinoma 8502/3

筛状癌Cribriform carcinoma 6201/3

印戒细胞/组织细胞样癌Signet-ring cell/histiocytoid carcinoma 8490/3

伴大汗腺和小汗腺化生的良性肿瘤

Benign tumours with apocrine and eccrine differentiation

汗腺囊瘤/囊腺瘤Hidrocystoma/cystadenoma 8404/0

汗管瘤Syringoma

汗孔瘤Poroma 8407/0

汗管纤维腺瘤Syringofibroadenoma 8409/0

汗腺瘤Hidradenoma 8392/0

螺旋腺瘤Spiradenoma 8402/0

圆柱瘤Cylindroma 8403/0

小管腺瘤Tubular adenoma 8200/0

乳头状汗管囊腺瘤Syringocystadenoma papilliferum 8211/0

混合瘤Mixed tumour 8406/0

肌上皮瘤Myoepithelioma8982/0

伴有毛囊分化恶性肿瘤Malignant tumours with follicular differentiation

毛母质癌;Pilomatrical carcinoma 6110/3

增生性毛外根鞘瘤 Proliferating trichilernmal turnour 8103/1

毛母细胞癌/癌肉瘤Trichoblastic carcinorna/carcinosarcoma 8100/3

外毛根鞘癌Trichilemmal carcinoma 8102/3

毛囊分化的良性肿瘤Benign tumours with follicular differentiation

毛母细胞瘤Trichoblastoma 8100/0 

毛母质瘤Pilomatricoma 8110/0

外毛根鞘瘤Trichilemmoma 8102/0

毛囊瘤Trichofolliculoma 8101/0

毛鞘棘皮瘤Pilar sheath acanthoma 8104/0

毛囊漏斗肿瘤Tumour of the follicular infundibulum 8104/0

黑素细胞基质瘤Melanocytic matricoma 8110/0

梭形细胞为主性毛盘瘤Spindle cell-predominant trichodiscoma 8391/0

伴皮脂腺分化的肿瘤Tumours with sebaceous differentiation

皮脂腺癌Sebaceous carcinoma 8410/3

皮脂腺腺瘤Sebaceous adenoma 8410/0

皮脂瘤Sebaceoma 8410/0

部位特异性肿瘤Site-specific tumours

乳腺PagetMammary Paget disease 8540/3

乳腺外PagetExtramammary Paget disease 8542/3

肛门生殖器乳腺样腺癌Adenocarcinoma of anogenital mammary-like glands 8500/3

乳头状汗腺瘤Hidradenoma papilliferum 8405/0

肛门生殖器乳腺样纤维腺瘤

Fibroadenoma of anogenital mammary-like glands 9010/0

肛门生殖器乳腺样叶状肿瘤

Phyllodes tumour of anogenital mammary-like glands 9020/0

造血和淋巴源性肿瘤Tumours of haematopoietic and lymphoid origin

蕈样霉菌Mycosis fungoides 9700/3 

亲毛囊性蕈样霉菌病Folliculotropic mycosis fungoides 9700/3

肉芽肿性皮肤松弛症Granulomatous slack skin 9700/3

佩吉特样网状细胞增多症Pagetoid reliculosis 9700/3

Sézary综合征Sézary syndrome 9701/3

原发皮肤CD30阳性T细胞淋巴增殖性疾病

Primary cutaneous CD30+ T-cell lymphoproliferative disorders

淋巴瘤样丘疹病Lymphomatoid papulosis 9718/1

原发性皮肤间变大细胞淋巴瘤

Primary cutaneous anaplastic large cell lymphoma 9718/3

皮肤成人T细胞白血病/淋巴瘤

Cutaneous adult T-cell leukaemia/lymphoma 9827/3

皮下质膜炎样T细胞淋巴瘤

Subcutaneous panniculitis-like T-cell lymphoma 9708/3

慢性活动性EB病毒感染皮肤表现

Cutaneous manifestations of chronic active EBV infection

种豆水疱病样淋巴增生性病变

Hydroa vacciniforme-like lymphoproliferative disorder 9725/1

结外NK/T细胞淋巴瘤,鼻型 Extranodal NK/T-cell lymphoma, nasal type 9719/3

原发皮肤外周T细胞淋巴瘤,罕见亚型

Primary cutaneous peripheral T-cell lymphomas,rare subtypes

原发皮肤gamma-delta T细胞淋巴瘤

Primary cutaneous gamma-delta T-cell lymphoma 9726/3

原发性皮肤CD8+亲表皮细胞毒性T细胞淋巴瘤Primary cutaneous CD8+ aggressive epidermotropic cytotoxic T-cell lymphoma 9709/3

原发性皮肤肢端CD8+T细胞淋巴瘤Primary cutaneous acral CD8+ T-celllymphoma 9709/3

原发性皮肤CD4+小/中型T细胞淋巴增生性疾病Primary cutaneous CD4+ small/medium T-cell lymphoproliferative disorder 9709/1

继发皮肤T细胞淋巴瘤和白血病Secondary cutaneous involvement in T-cell lymphomas and leukaemias

系统性间变大细胞淋巴瘤,ALK阳性

Systemic anaplastic large cell lymphoma.ALK-positive 9714/3

系统性间变大细胞淋巴瘤,ALK阴性

Systemic anaplastic large cell lymphoma,ALK-negative 9715/3

血管免疫母细胞性T细胞淋巴瘤Angioimnunoblastic T-cell lymphoma 9705/3

T细胞幼淋巴细胞性白血病T-cell prolymphocytic leukaemia 9834/3

原发性皮肤边缘区淋巴瘤Primary cutaneous marginal zone(MALT) lymphorna 9699/3

原发性皮肤滤泡中心淋巴瘤Prinary cutaneous follicle centre lymphoma 9597/3

原发性皮肤弥漫性大B细胞淋巴瘤,腿型 Primary cutaneous diffuse large B-cell lymphoma, leg type 9680/3

血管内大B细胞淋巴瘤Intravascular large B-cell lymphoma 9712/3

EB病毒阳性黏膜皮肤溃疡EBV-positive mucocutaneous ulcer 9680/1

淋巴瘤样肉芽肿Lymphomatoid granulomatosis 

Grade 1-2 9766/1

Grade 3 9766/3

皮肤外B细胞淋巴瘤/白血病累及皮肤Cutaneous involvement in primarily extracutaneous B-cell lymphomas and leukaemias

套细胞淋巴瘤Mantle cell lymphoma 9673/3

Burkitt淋巴瘤Burkitt lymphoma 9687/3

慢性淋巴细胞性白血病/B小淋巴细胞性淋巴瘤Chronic lymphocytic leukaemia/small lymphocytic lymphoma 9823/3

T淋巴母和B淋巴母细胞性白血病/淋巴瘤

T-lymphoblastic and B-lymphoblasticleukaemia/lymphoma

T淋巴母细胞性白血病/淋巴瘤

T-lymphoblastic leukaemia/lymphoma 9837/3

B淋巴母细胞性白血病/淋巴瘤

B-lymphoblastic leukaenia/lymphoma 9811/3

母细胞性浆样树突状细胞肿瘤Blastic plasmacytoid dendritic cell neoplasm 9727/3

髓系白血病累及皮肤Cutaneous involvement in myeloid leukaemia 9930/3

皮肤肥大细胞增多症Cutaneous mastocytosis 9740/1

肥大细胞肉瘤Mast cell sarcoma 9740/3

惰性系统性肥大细胞增多症Indolent systemic mastocytosis 9741/1

侵袭性系统性肥大细胞增多症Aggressive systemic mastocytosis 9741/3

系统性肥大细胞增多症伴造血系统肿瘤Systemic mastocytosis with an associated haematological neoplasm 9741/3

肥大细胞白血病Mast cell leukaemia 9742/3


组织细胞和树突状细胞肿瘤Histiocytic and dendritic cell neoplasms

朗格汉斯组织细胞增多症Langerhans cell histiocytosis 9751/1

不确定细胞组织细胞增多症/不确定树突细胞肿瘤

Indeterminate cell histiocytosis/ indeterminate dendritic cell tumour 9757/3

Rosai-DorfmanRosai-Dorfman disease

幼年性黄色肉芽肿Juvenile xanthogranuloma

 脂质肉芽肿病Erdheim-Chester disease 9749/3

网状组织细胞增多症Reticulohistiocytosis 8831/0



软组织和神经肿瘤Soft tissue and neural tumours

脂肪细胞肿瘤Adipocytic tumours

非典型脂肪瘤性肿瘤Atypical lipomatous tumour 8850/1

去分化脂肪瘤Dedifferentiated liposarcoma 8858/3

多形性脂肪肉瘤Pleomorphic liposarcoma 8854/3

脂肪瘤Lipoma 8850/0

梭形细胞/多形性脂肪瘤Spindle cell/pleomorphic lipoma 8857/0

血管脂肪瘤Angiolipoma 8861/0

表浅脂肪瘤性痣Naevus lipomatosus superficialis


纤维母细胞、肌纤维母细胞和纤维组织细胞肿瘤

Fibroblastic, myofibroblastic, and fibrohistiocytic lumours

黏液炎性纤维母细胞肉瘤Myxoinllammatory fibroblastic sarcoma 8811/1

隆突性皮肤纤维肉瘤Dermatolibrosarcoma protuberans 8832/1

巨细胞纤维母细胞瘤Giant cell fibroblastoma 8834/1

Bednar瘤Bednar tumour 8833/1

纤维肉瘤性隆突性皮肤纤维肉瘤

Fibrosarcomatous dermatofibrosarcoma protuberans 8832/3

丛状纤维组织细胞瘤Plexiform fibrohistiocytic tumour 8835/1

表浅纤维瘤病Superficial fibromatosis 8813/1

皮肤纤维瘤(纤维组织细胞瘤)Dermatofibroma (fibrous histiocytoma) 8832/0

上皮样纤维组织细胞瘤Epithelioid fibrous histiocytoma 8830/0

纤维瘤Fibromas

腱鞘纤维瘤Fibroma of tendon sheath 8813/0

钙化性腱膜纤维瘤Calcilying aponeurotic fibroma 8816/0

硬化性纤维瘤Sclerotic fibroma 8823/0*

Nuchal型纤维瘤Nuchal-type fibroma 8810/0

Gardne纤维瘤Gardner fibroma 8810/0

多形性纤维瘤Pleomorphic fibroma 8832/0

弹力纤维Elastofibroma 8820/0

胶原纤维瘤Collagenous fibroma  8810/0

浅表肢端纤维黏液瘤Superficial acral fibromyxoma  8811/0

皮肤黏液瘤Cutaneous myxoma 8840/0

皮肤肌纤维瘤Dermatomyofibroma 8824/0

肌纤维瘤Myofibroma 8824/0

肌纤维瘤病Myofibromatosis 8824/1

斑块状CD34+真皮纤维瘤Plaque-like CD34+ dermal fibroma 8810/0

结节性筋膜炎Nodular fasciitis 8828/0


平滑肌肿瘤Smooth muscle tumours

皮肤平滑肌瘤Cutaneous leiomyoma 8890/0

皮肤平滑肌肉瘤(非典型平滑肌肿瘤)

Cutaneous leiomyosarcoma (atypical smooth muscle tumour) 8897/1


(肌)周细胞肿瘤(Myo)pericytic tumours

血管球留Glomus tumour 8711/0

静脉球畸形(球血管肌瘤)

Glomuvenous malformation(glomangiomyoma)8713/0

恶性潜能未定的血管球肿瘤

Glomus tumour of uncertain malignant potential 8711/1*

恶性血管球瘤Malignant glomus tumour 8711/3

肌周细胞瘤Myopericytoma 8824/0

血管平滑肌瘤Angioleiomyoma 8894/0


血管肿瘤Vascular tumours

皮肤血管肉瘤Cutaneous angiosarcoma 9120/3

血管内皮瘤Haemangioendotheliomas

混合型血管内皮瘤Composite haemangioendothelioma 9136/1

卡波西样血管内皮瘤Kaposiform haemangioendothelioma 9130/1

假肌源性血管内皮瘤Pseudomyogenic haemangioendothelioma 9138/1

网状血管内皮瘤Retiform haemangioendothelioma 9136/1

上皮样血管内皮瘤Epithelioid haemangioendothelioma 9133/3

卡波西肉瘤Kaposi sarcoma 9140/3

非典型血管病变Atypical vascular lesion 9126/0*

皮肤上皮样血管瘤样结节

Cutaneous epithelioid angiomatous nodule 9125/0

血管瘤Haemangiomas

樱桃血管瘤Cherry haemangioma 9120/0

窦性血管瘤Sinusoidal haemangioma 9120/0

微静脉血管瘤Microvenular haemangioma 9120/0

鞋钉样血管瘤Hobnail haemangioma 9120/0

肾小球样Glomeruloid haemangioma 9120/0

梭形细胞血管瘤Spindle cell haemangiama 9120/0

上皮样血管瘤Epithelioid haemangioma 9125/0

簇状血管瘤Tufted haemangioma 9161/0

血管角皮瘤Angiokeratoma 9141/0

幼年性血管瘤Infantile haemangioma 9131/0

快速退化性先天性血管瘤

Rapidly involuting congenital haemangioma 9131/0

非退化性先天性血管瘤Non-involuting congenilal haemangioma 9131/0

分叶状毛细血管瘤Lobular capillary haemangioma 9131/0

疣状静脉畸形Verrucous venous malformation 9142/0

动静脉畸形Arteriovenous malformation 9123/0

淋巴管瘤(浅表淋巴管畸形)

Lymphangioma (superficial lymphatic malformation) 9170/0


神经肿瘤Neural tumours

神经纤维瘤Neurofibroma 9540/0

孤立性局限性神经瘤Solitary circumscribed neuroma 9570/0

皮肤神经鞘瘤Dermal nerve sheath myxoma  9562/0

神经束膜瘤Perineurioma 9571/0

恶性神经束膜瘤Malignant perineurioma 9571/3

颗粒细胞瘤Granular cell tumour 9580/0

恶性颗粒细胞瘤Malignant granular cell tumour 9580/3

神经鞘瘤Schwannoma 9560/0

恶性外周神经鞘瘤Malignant peripheral nerve sheath tumour 9540/3

上皮样恶性神经鞘瘤

Epithelioid malignant peripheral nerve sheath tumour 9542/3

恶性蝾螈瘤Malignant triton tumour 9561/3


分化不明肿瘤Tumours of uncertain differentiation

非典型纤维黄色瘤Atypical fibroxanthoma 8830/1

多形性皮肤肉瘤Pleomorphic dermal sarcoma 8802/3

黏液纤维肉瘤Myxofibrosarcoma 8811/3

上皮样肉瘤Epithelioid sarcoma 8804/3

皮肤透明细胞肉瘤Dermal clear cell sarcoma 9044/3

尤文肉瘤Ewing sarcoma 9364/3

原始非神经颗粒细胞瘤Primitive non-neural granular cell tumour 6990/1

细胞性神经鞘瘤Cellular neurothekeoma 9562/0


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